The World of Collagen – Poster
The World of Collagen – Poster

The World of Collagen – Poster

  The World of Collagen. We present a pictorial overview of Collagen that demonstrates the far-reaching impact and potential of this important family of proteins. We see the supply of collagen, be that research-grade or for clinical applications moving from the established Type I bovine to recombinant synthetic biology forms and animal-free systems. ProColl is […]
Date: Wednesday July 13, 2022
Alternatives to scarce Matrigel and why they are needed.
Alternatives to scarce Matrigel and why they are needed.

Alternatives to scarce Matrigel and why they are needed.

Matrigel, first developed over 35 years ago has been used in 2D and 3D cell culture, however due to supply limitations, inconsistency of biochemical and mechanical properties and potential for antigenicity, researchers are now looking to other biomaterials for structural support of their cultures. This ProColl white paper examines the reasons for Matrigel’s limitations and […]
Date: Wednesday June 1, 2022
ProColl Research Grade Collagen Gelling Protocol – Cross linker free
ProColl Research Grade Collagen Gelling Protocol – Cross linker free

ProColl Research Grade Collagen Gelling Protocol – Cross linker free

When using acid soluble collagen, pH neutralisation in buffered conditions causes the collagen molecules to become insoluble and aggregate to form a gel when the pH is neutral. This forms a weak gel and chemical cross-linking is recommended to produce a stiffer gel that is better suited to the cell growth application. When a higher […]
Date: Wednesday June 1, 2022
ProColl Research Grade Collagen Gelling Protocol – Genipin Cross linker
ProColl Research Grade Collagen Gelling Protocol – Genipin Cross linker

ProColl Research Grade Collagen Gelling Protocol – Genipin Cross linker

Often the application of collagen requires the production of a structure that is mechanically robust. This can be achieved through a process of cross-linking functional groups on the collagen molecules. When using acid soluble collagen, the collagen molecules become insoluble and aggregates to form a gel when the pH is increased. However, this is a […]
Date: Wednesday May 11, 2022
ISO 13485 Coming Soon
ISO 13485 Coming Soon

ISO 13485 Coming Soon

We are excited to announce that we are working with BS Partnership Ltd to implement our quality management system for ISO 13485 compliance. The completion of this process will enable ProColl collagen to be integrated into medical devices. We expect to have a successful audit completed by the end of this summer.
Date: Wednesday January 12, 2022
Structured Collagen Superior to Gelatin for Cell Culture
Structured Collagen Superior to Gelatin for Cell Culture

Structured Collagen Superior to Gelatin for Cell Culture

Research by Sheffield University using ProColl’s acid soluble collagen demonstrated its superior performance over gelatin for cell culture. Using ProColl’s collagen resulted in cells with significantly better levels of key bone-growth markers. Calcium content and DNA were significantly higher when cultured on ProColl’s collagen than gelatin. Also, significantly lower collagen production occurred since the closer-to-native […]
Date: Tuesday January 11, 2022
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Animal Free & Bovine Collagen Products


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