Collagen and Wound Healing – The Impact of Single Alpha Chain Collagen.
Collagen is key to restoring structure in wounds, given both its abundance as the most common protein in animals and innate interaction with various parts of the wound healing cascade. When collagen is damaged, individual chains that make up the triple helix become exposed which the body then identifies as needing repair.
ProColl has a patent pending product, termed single alpha chain collagen, and this whitepaper presents research by the accelerate project of the healthcare technology centre in Swansea, which demonstrates that the presence of single alpha chain collagen up-regulates the expression of interleukins IL-6 and IL-8 in the same way that exposed strands of collagen would in nature, when collagen is damaged by injury. This has the potential benefit of accelerating the healing process. This property can be exploited by incorporating single chain collagen in wound treatment products to gain accelerated wound healing, while the solubility and reformation of the single alpha chains under physiological conditions could also yield a stable collagen supply to the wound bed.
Read the whitepaper here: Mobile users click the link below.
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